Developing future therapies for inoperable cancers

An innovative radiation treatment that could one day be a valuable addition to conventional radiation therapy for inoperable brain and spinal tumors is a step closer, thanks to new research led by University of Saskatchewan (USask) researchers at the Canadian Light Source (CLS).

Chicilo, F., et al. Physics in Medicine & Biology 65, no. 7 (2020): 075010.

BMIT eNews | Spring, 2020

- COVID-19 Call for Proposals (Deadline May 21) - Remote Access for microCT Data Reconstruction and Visualization Server - New Technique: Laminography - 300 Publications and Counting! - Cycle 32 Call for Proposals Results  - Around the Beamlines - Pictures of the Season

Remote access for microCT data reconstruction and visualization server

Together with IT group at CLS we have enabled remote access to one of our reconstruction servers. Users can obtain remote access to 5-10 data sets at a time, reconstruct data, and use Avizo for visualization and data analysis directly on BMIT server. Please contact Dr. Adam Webb ( for details and scheduling. Depending on the number of requests access duration may be limited to 2-3 days.

Baking the Perfect Loaf

Ever since early humans discovered how to grind grain, the art of breadmaking has flourished and today bread is the most widely consumed food in the world. The apron has now been replaced by the lab coat as scientists seek to understand the intricacies of creating healthier, more consistent commercial bread products that meet changing consumer demands.

Sun, Xinyang, et al., The effects of sodium reduction on the gas phase of bread doughs using synchrotron X-ray microtomography. Food Research International (2019)

Wide field imaging energy dispersive X-ray absorption spectroscopy

Based on spectral K-edge subtraction imaging (developed at CLS-BMIT), a new energy dispersive X-ray absorption spectroscopy method is developed at BMIT-BM beamline for simultaneous wide-field imaging and transmission X-ray Absorption Spectroscopy (XAS). Sufficient energy and spatial resolution are demonstrated for both full field imaging and computed tomography in quantifying selenium chemical species.

BMIT eNews | Fall 2019

- CT Data Processing Using UFO-KIT and Dragonfly (May 20-22, 2020) - 10X magnification capability is now available - Cycle 32 Call for Proposals - Important Notes for Preparation of Proposals - Around the Beamlines - Pictures of the Season - Upcoming Conferences

3D Imaging of Hydrogen Induced Cracking in Pipeline Steel

Synchrotron 3D computed tomography (CT) at BMIT-ID beamline at Canadian Light Source was used to explain the features of the HIC cracks formation during tensile tests.

Visualization of 3D Bioprinted Tissue Scaffolds Using Synchrotron-Based Phase Contrast Imaging

We developed the synchrotron-based x-ray inline phase contrast imaging-computed tomography (SR-inline-PCI-CT) at the Biomedical Imaging and Therapy (BMIT) Facility of Canadian Light Source to visualize the printed hydrogel-based scaffolds. 

The BMIT facility at the Canadian Light Source is specifically designed to support a wide variety of programs in the life sciences, and provides outstanding possibilities for research, including potential clinical applications in imaging and radiation therapy. The facility has two beamlines; a bend magnet beamline, 05B1-1, and an insertion device beamline, 05ID-2. The BMIT advanced imaging modalities allow biomedical systems to be visualized in ways not possible using conventional clinical systems. These can provide insight into anatomy, function, visualization of disease processes including therapeutic response and the possibility of repeated imaging at low dose.

List of Publications »

  • Ren, Yikai; Stobbs, Jarvis A.; Lee, Dong-Jin; Li, Dongxing; Karunakaran, Chithra et al. (2024). Utilizing Synchrotron-Based X-ray Micro-Computed Tomography to Visualize the Microscopic Structure of Starch Hydrogels In Situ. Biomacromolecules . 10.1021/acs.biomac.3c01438.
  • Kalugin, Denis; Bahig, Jumanah; Shoker, Ahmed; Doan, Huu; Kirychuk, Shelley et al. (2024). Superhydrophobic polyether sulfone (PES) dialysis membrane with enhanced hemocompatibility and reduced human serum protein interactions: Ex vivo, in situ synchrotron imaging, experimental, and computational studies. Separation and Purification Technology 335, 126071. 10.1016/j.seppur.2023.126071.
  • Nabipoor Hassankiadeh, Mojtaba; Heydari, Mohammad Mehdi; Blocka, Carter; Zhang, Lifeng (2024). Synchrotron X-ray micro-computed tomography imaging of solid bridges between potash particles near contact points. Particuology 92, 24-29. 10.1016/j.partic.2024.04.012.